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Oct. 25, 2018 (MedicalXpress) -- Scientists at The University of Manchester have shown for the first time how antibiotics can predispose the gut to avoidable infections that trigger bowel disease in mice.
The team, led by Dr. Elizabeth Mann, also showed that substances derived from fiber prevent this damage to the gut, suggesting a high-fiber diet could be useful when taken during and after a course of antibiotics.
The research is to be published in Science Translational Medicine and funded by the Wellcome Trust and the Medical Research Council.
They tested broad-spectrum antibiotics on mice to assess their impact on the gut's microbiota, the community of microbes that live in the gastrointestinal tract.
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