A pair of naturally occurring antibodies are able to kill more than 90% of all strains of HIV, researchers say. The finding could lead to the development of new treatments and a possible vaccine.
July 9, 2010 (Los Angeles Times) -- An effective vaccine against the AIDS virus may have moved one step closer to reality, researchers said Thursday.
Federal researchers have identified a pair of naturally occurring antibodies that are able to kill more than 90% of all strains of the AIDS virus, a finding they say could lead to the development of new treatments for HIV infections and to the production of the first successful vaccine against the virus.
HIV, the virus that causes AIDS, is notoriously mutable, changing the composition of proteins on its surface with ease to escape pressure from the immune system. This enables it to continue infecting cells even after the appearance of antibodies targeting it — and to avoid the relatively ineffective vaccines developed so far.
Hundreds of variants of the virus are now in circulation around the world, and the identification of so-called broadly neutralizing antibodies that can block the bulk of them has been the holy grail of HIV researchers.
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